Prof. Colin Doherty
About Colin
Prof. Colin Doherty is a consultant neurologist, epilepsy specialist, and director of the epilepsy service at St James's Hospital, Dublin, Ireland. He served as the national clinical lead for the Epilepsy Care Programme in Ireland for nine years, with a charge to develop epilepsy services nationally to improve quality of care and access for patients. He has recently moved from that role to take up a specific remit around women’s health in epilepsy with the evolution of the valproate in pregnancy story.
Colin completed his undergraduate degree at University College Dublin in 1991. He trained in medicine and neurology at St Vincent’s and Beaumont Hospitals and later at the Partners Neurology Residency Programme at Harvard Medical School, Boston (Brigham and Women’s Hospital and Massachusetts General Hospital), where he was Chief Resident (1998-2001). He then completed fellowships in epilepsy and cognition at Massachusetts General Hospital (2001-2003).
He has published widely in the areas of brain imaging in epilepsy, the genetics of epilepsy, functional imaging of language, dementia, clinical neurology and epileptology and traumatic brain injury. In the last few years he has become interested in the challenges of population health, health services research and care delivery in epilepsy. He published recently on national issues regarding epilepsy care including; traumatic brain injury, evidence based pathways, national mortality estimates, hospital access restrictions and national prescribing rates. He has 105 peer reviewed publications, 4211 citations, a H-index of 35 and i10index of 78. Between co-applicant, Co-PI and PI grant applications he has been collaboratively responsible for 7 Million EU in funding I has authored chapters in three textbooks and co-edited one.
Colin was a member of the Irish government's expert group on resource allocation in the health sector (2011). He was a member of the National Clinical Effectiveness Committee in Ireland since its inception in 2011 to 2015 and represented the RCPI on The Irish Patient Safety Steering Group 2012-2016. He was a board member of the Health Research Board (2010-15) and is a founder member and Medical Director of Epilepsy Research Ireland (ERI). He is the Irish representative to the International League Against Epilepsy (ILAE) committee for the Global Campaign Against Epilepsy and a co-applicant on a large EU funded study on the epidemiology of epilepsy in Europe (ESBASE). He was National Clinical Lead for the Epilepsy Care Programme in Ireland from 2010-2018, with a charge to develop epilepsy services nationally to improve quality of care and access for patients. He has recently moved from that role to take up a specific remit around Women's Health in Epilepsy with the evolution of the Valproate in Pregnancy story.
He states that he has learned a lot in the last five years about the urgent issue of healthcare reform and see medical education, both postgraduate and undergraduate in urgent need of firstly protection of its core mission and values but also innovation and development to meet the challenges of 21st century medical care: Amongst the challenges are underpinning the funding of basic, translation and clinical research; Teamwork and its effect of professionalism, the role of the patient in the design and delivery of healthcare, and the rise of technology.
Areas of focus
Epilepsy
Traumatic Brain Injury
Population health
Care delivery
Professional memberships
Member of the Irish government’s expert group on resource allocation in the health sector (2011-present)
Member of the National Clinical Effectiveness Committee in Ireland since its inception in 2011 (2011-2015)
Represented the Royal College of Physicians of Ireland on The Irish Patient Safety Steering Group (2012-2016)
Board member of the Health Research Board (2010-2015)
Founder member and medical director of Epilepsy Research Ireland (ERI)
Irish representative to the International League Against Epilepsy Committee (ILAE) for the global campaign against epilepsy and a collaborator on a large EU-funded study on the epidemiology of epilepsy in Europe (ESBASE)
Principal Investigator (PI) at the Science Foundation Ireland (SFI) research centre FutureNeuro
Episodes
Is A Blood-Brain Barrier Leak Causing Seizures?
02 July 2026
In this episode we discuss how:
Inflammation and the blood-brain barrier may explain why some seizures remain uncontrolled
Steroids may temporarily improve seizure control
Future immunotherapies could help some whose seizures not responding to current treatments.
Tune in here 👇
🎬 YouTube 🎧 Podcast 📄Transcript
Could Immunotherapy Control Seizures?
25 June 2026
In this episode we discuss how:
The immune system could be part of why some seizures remain uncontrolled.
Early immunotherapy studies produced promising results in some highly refractory epilepsies.
Autoimmune epilepsies may require very different treatment approaches.
Tune in here 👇
🎬 YouTube 🎧 Podcast 📄Transcript
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Could immunotherapy be a feasible treatment option for patient's suffering from chronic epilepsy?
Immunotherapy, Colin P. Doherty
PMID: 42053207, PMCID: PMC13182960 (available on 2027-04-29), DOI: 10.1080/1750743X.2026.2665027